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Herbal medicine improves the efficacy of antibiotics to treat sepsis

(CC BY-SA 3.0) by James Heilman, MD

A research team from Xinhua Hospital affiliated with Shanghai Jiaotong University carried out a prospective, randomized, placebo-controlled trial to investigate the efficacy and safety of Shufeng Jiedu Capsules(SFJDC) in the treatment of sepsis ​(Liu et al. 2020)​ . 129 hospitalized patients met the inclusion criteria were randomised to either the combination group i.e. antibiotic plus SFJDC (n = 66) or a single antibiotics group (n = 63). The APACHE II score, TCM symptom score, CRP, neutrophil-lymphocyte ratio (NLR), and healing rate differed significantly between the two groups on the 7th day of hospitalization. They concluded that the combination of antibiotics and SFJDC in the treatment of sepsis was superior to routine antibiotic treatment since combination therapy reduced the inflammatory response and improves prognosis for septic patients.

Herbs in SFJDC

Huzhang (Polygonum cuspidatum) Lianqiao (Forsythia) Banlangeng (Radix) Caihu(Bupleurum) Baijiangcao (Sabina) Mabiancao (Verbena) Lugeng (Reed Root) Gancao (Licorice)


Liu, Yuqi, Yun Yu, Hui Dai, and Aihua Fei. 2020. “Efficacy of Shufeng Jiedu Capsules in the Treatment of Sepsis: A Prospective, Randomized, Placebo-Controlled Trial.” European Journal of Integrative Medicine, July, 101172.


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